Side Effects of Men Taking Female Birth Control Pills. Female birth control pills are intended to prevent contraception in women. They are most often a combination of synthetic forms of both types of female hormones, estrogen and progesterone. Although rarely used, female hormones may be taken by men for a number of medical conditions such as prostate enlargement, testicular cancer and aromatase deficience. Because oral contraceptives are not intended for use in men, side effects have not been well studied or documented however, they may cause a number of adverse effects in men similar to those seen with the use of other female hormones. Testosterone is responsible for the formation and development of male sex characteristics. When testosterone is opposed by high levels of female hormones present in birth control pills, testosterone will be less effective. Men who take female birth controls may experience changes in the functioning and physical appearance of their sex organs. Risks may include lowered sperm count, decreased libido, erectile dysfunction and shrinking testes size. Some men may also develop breast tissue, known as gynecomastia, along with enlargement and darkening of the nipples. Testosterone is largely responsible for the greater growth of muscle tissue and bone tissue in men. Download Minitool Power Data Recovery V6 5. Note that there are non PMU based substitutes for PMUderived estrogen. Prescribed for Menopause symptoms moderate to severe and the prevention of. With the use of female birth control pills, testosterone will be less effective, and large muscle groups such as the legs, chest and arm muscles, may decrease in size. In addition, the bones may develop a condition similar to osteoporosis, becoming more porous and brittle. This may increase the risk of bone fracture. Fat storage may also be affected, leading to a feminization of the physical appearance. Facial and body hair may also decrease in thickness and growth, although male pattern baldness may improve somewhat. Testosterone is thought to play a role in male assertiveness and aggressive tendencies. As testosterone effectiveness is decreased by taking female hormones such as birth control pills, men may become less assertive. Some men may also lose interest in sex and other pleasurable activities while taking female birth control pills, due to both hormonal influence but also because of depression that may develop from self esteem issues related to physical changes. Hot flashes and other symptoms such as insomnia and foggy thinking, usually experienced by women, may also occur. The development of breast tissue may increase the risk of the development of male breast tissue. Birth control pill usage may also increase the risk of the development of hormone related blood clots, particularly in those who smoke. Men who take female hormones, including birth control pills, may also increase the chance for developing liver and gallbladder disease. There may be, however, a decrease in the chance of prostate enlargement and cancer. Estrogen Patch Side Effects On Men' title='Estrogen Patch Side Effects On Men' />Side Effects Of Taking Cholesterol Medication What Is The Best Fat Burning Pills For Men Natural Fat Burners For Stomach Fat. Estrogens are a group of hormones that that are important for female sexual and reproductive development. FDA prescribing information, side effects and uses. Vivelleestradiol transdermal system. Continuous delivery for twice weekly application. Rx only. Prescribing Information. ESTROGENS INCREASE THE RISK OF ENDOMETRIAL CANCERClose clinical surveillance of all women taking estrogens is important. Adequate diagnostic measures, including endometrial sampling when indicated, should be undertaken to rule out malignancy in all cases of undiagnosed persistent or recurring abnormal vaginal bleeding. WebMDs guide to various estrogen replacement treatments, including the pros and cons of each. Background The efficacy and safety of testosterone treatment for hypoactive sexual desire disorder in postmenopausal women not receiving estrogen therapy are unknown. DHEA supplement benefit side effects, dosage 5 mg 10 mg 25 mg, 50 mg memory, libido, hair loss, prostate. Hormone therapy refers to treating menopause symptoms with either estrogen or combined estrogenprogesterone. This hormone therapy is for women, though it has been. There is currently no evidence that the use of natural estrogens results in a different endometrial risk profile than synthetic estrogens at equivalent estrogen doses. See WARNINGS, Malignant Neoplasms,Endometrial Cancer. CARDIOVASCULAR AND OTHER RISKSEstrogens with or without progestins should not be used for the prevention of cardiovascular disease. See WARNINGS, Cardiovascular Disorders. The Womens Health Initiative WHI study reported increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis in postmenopausal women 5. CE 0. 6. 25 mg combined with medroxyprogesterone acetate MPA 2. See CLINICAL PHARMACOLOGY, Clinical Studies. The Womens Health Initiative Memory Study WHIMS, a substudy of WHI, reported increased risk of developing probable dementia in postmenopausal women 6. It is unknown whether this finding applies to younger postmenopausal women or to women taking estrogen alone therapy. See CLINICAL PHARMACOLOGY, Clinical Studies. Other doses of oral conjugated estrogens with medroxyprogesterone acetate, and other combinations and dosage forms of estrogens and progestins were not studied in the WHI clinical trials and, in the absence of comparable data, these risks should be assumed to be similar. Because of these risks, estrogens with or without progestins should be prescribed at the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman. Vivelle Description. The Vivelle estradiol transdermal system contains estradiol in a multipolymeric adhesive. The system is designed to release estradiol continuously upon application to intact skin. Five systems are available to provide nominal in vivo delivery of 0. Each corresponding system having an active surface area of 7. USP, respectively. The composition of the systems per unit area is identical. Estradiol USP is a white, crystalline powder, chemically described as estra 1,3,51. The structural formula is      The molecular formula of estradiol is C1. H2. 4O2. The molecular weight is 2. The Vivelle system comprises three layers. Proceeding from the visible surface toward the surface attached to the skin, these layers are 1 a translucent flexible film consisting of an ethylene vinyl alcohol copolymer film, a polyurethane film, urethane polymer and epoxy resin, 2 an adhesive formulation containing estradiol USP, acrylic adhesive, polyisobutylene, ethylene vinyl acetate copolymer, 1,3 butylene glycol, styrene butadiene rubber, oleic acid NF, lecithin, propylene glycol, bentonite NF, mineral oil USP, and dipropylene glycol, and 3 a polyester release liner that is attached to the adhesive surface and must be removed before the system can be used. The active component of the system is estradiol. The remaining components of the system are pharmacologically inactive. Vivelle Clinical Pharmacology. Endogenous estrogens are largely responsible for the development and maintenance of the female reproductive system and secondary sexual characteristics. Learn about Menostar Estradiol Transdermal System may treat, uses, dosage, side effects, drug interactions, warnings, patient labeling, reviews, and related. The combined oral contraceptive pill COCP, often referred to as the birth control pill or colloquially as the pill, is a birth control method that includes a. Treatment. There are many formulations and dosages of estrogen and estrogenprogestin combinations on the market today for treating conditions that result from. Although circulating estrogens exist in a dynamic equilibrium of metabolic interconversions, estradiol is the principal intracellular human estrogen and is substantially more potent than its metabolites, estrone and estriol, at the receptor level. The primary source of estrogen in normally cycling adult women is the ovarian follicle, which secretes 7. After menopause, most endogenous estrogen is produced by conversion of androstenedione, secreted by the adrenal cortex, to estrone by peripheral tissues. Thus, estrone and the sulfate conjugated form, estrone sulfate, are the most abundant circulating estrogens in postmenopausal women. Estrogens act through binding to nuclear receptors in estrogen responsive tissues. To date, two estrogen receptors have been identified. These vary in proportion from tissue to tissue. Circulating estrogens modulate the pituitary secretion of the gonadotropins, luteinizing hormone LH and follicle stimulating hormone FSH through a negative feedback mechanism. Estrogens act to reduce the elevated levels of these hormones seen in postmenopausal women. Pharmacokinetics. Absorption. In a multiple dose study consisting of three consecutive patch applications of the Vivelle system, which was conducted in 1. Patches that deliver nominal estradiol doses of approximately 0. These systems increased estradiol levels above baseline within four hours and maintained respective mean levels of 2. Estrogen Patch Side Effects On Men' title='Estrogen Patch Side Effects On Men' />L above baseline following application to the abdomen slightly higher mean levels of 8. L above baseline were observed following application to the buttocks. At the same time, increases in estrone plasma concentrations averaged about 1. L, respectively, following application to the abdomen and 6. L for the buttocks. While plasma concentrations of estradiol and estrone remained slightly above baseline at 1. The figure see Figure 1 illustrates the mean plasma concentrations of estradiol at steady state during application of these patches at four different dosages. Figure 1. Steady State Estradiol Plasma Concentrationsfor Systems Applied to the Abdomen. Nonbaseline Corrected Levels      The corresponding pharmacokinetic parameters are summarized in Table 1 below. Table 1. Steady State Estradiol Pharmacokinetic Parametersfor Systems Applied to the Abdomenmean standard deviationNonbaseline Corrected DataDosagemgdayCmaxpgm. LCavgpgm. LCmin 8. L0. 0. 37. 54. 6 1. Mean baseline estradiol concentration 1. LPeak plasma concentrationAverage plasma concentrationMinimum plasma concentration at 8. Measured over 8. 0 hrApplied to the buttocks. Distribution. The distribution of exogenous estrogens is similar to that of endogenous estrogens. Estrogens are widely distributed in the body and are generally found in higher concentrations in the sex hormone target organs. Estrogens circulate in the blood largely bound to sex hormone binding globulin SHBG and albumin. Metabolism. Exogenous estrogens are metabolized in the same manner as endogenous estrogens. Circulating estrogens exist in a dynamic equilibrium of metabolic interconversions. These transformations take place mainly in the liver. Estradiol is converted reversibly to estrone, and both can be converted to estriol, which is the major urinary metabolite. Estrogens also undergo enterohepatic recirculation via sulfate and glucuronide conjugation in the liver, biliary secretion of conjugates into the intestine, and hydrolysis in the gut followed by reabsorption. In postmenopausal women, a significant proportion of the circulating estrogens exist as sulfate conjugates, especially estrone sulfate, which serves as a circulating reservoir for the formation of more active estrogens. Excretion. Estradiol, estrone, and estriol are excreted in the urine along with glucuronide and sulfate conjugates.